Looks like Nintendo is making about $40 per console sold, and the stores make about $50.

Here’s the numbers that just came out on the cost of the pieces included in the Wii

Graphic chip $29.60
CPU $13.00
DRAM $7.80
Optical disk drive $31.00
Power supply $11.30
Manufacturing cost $19.50

Cost total $158.30

Wholesale price $195.99

source: Kotaku